Adipokines

• Serum adipokines are associated with cholesterol metabolism in the metabolic syndrome.
  Hallikainen M, et al., Clin Chim Acta. 2007 Aug;383(1-2):126-32. Epub 2007 May 18.

Adipose Tissue Disorders

• Dissociation between adipose tissue expression and serum levels of adiponectin during and after diet-induced weight loss in obese subjects with and without the metabolic syndrome.
  Behre CJ, et al., Metabolism. 2007 Aug;56(8):1022-8.

Cardiovascular Disease

• Metabolic syndrome increases operative mortality in patients undergoing coronary artery bypass grafting surgery.
  Echahidi N, et al. J Am Coll Cardiol. 2007 Aug 28;50(9):843-51. Epub 2007 Aug 13.
• Serum C-reactive protein levels correlates better to metabolic syndrome defined by International Diabetes Federation than by NCEP ATP III in men.
  Lin MS, et al., Diabetes Res Clin Pract. 2007 Aug;77(2):286-92. Epub 2007 Jan 16.
• Systemic inflammation and metabolic syndrome in cardiac allograft vasculopathy.
  Raichlin ER, et al.,J Heart Lung Transplant. 2007 Aug;26(8):826-33.
• Coronary plaque vulnerability in metabolic syndrome: assessment of carotid artery morphology in acute coronary syndrome.
  Kato M, et al, Circ J. 2007 Aug;71(8):1229-33.
• Circulating leptin levels predict the development of metabolic syndrome in middle-aged men: an 8-year follow-up study.
  Galletti F, et al., J Hypertens. 2007 Aug;25(8):1671-7.
• Small dense low-density lipoprotein cholesterol is a useful marker of metabolic syndrome in patients with coronary artery disease.
  Nozue T, et al.,J Atheroscler Thromb. 2007 Aug;14(4):202-7. Epub 2007 Aug 14.
• Inflammation, the metabolic syndrome, and risk of coronary heart disease in women and men.
  Pischon T, et al.,Atherosclerosis. 2007 Aug 1; [Epub ahead of print]
• Clinical impact of metabolic syndrome by modified NCEP-ATPIII criteria on carotid atherosclerosis in Japanese adults.
  Teramura M, et al., J Atheroscler Thromb. 2007 Aug;14(4):172-8. Epub 2007 Aug 14.
• Severity of metabolic syndrome unfavorably influences oxidative stress and fatty acid metabolism in men.
  Zak A, et al., Tohoku J Exp Med. 2007 Aug;212(4):359-71.

Diabetes

• Metabolic syndrome, insulin resistance, and atherosclerosis in Japanese type 2 diabetic patients.
  Taniguchi A, et al., Metabolism. 2007 Aug;56(8):1099-103.
• Metabolic syndrome is not associated with markers of subclinical atherosclerosis, serum adiponectin and endogenous androgen concentrations in Japanese men with Type 2 diabetes.
  Fukui M, et al., Diabet Med. 2007 Aug;24(8):864-71. Epub 2007 Jun 25.
• Stroke presentation in Type 2 diabetes and the metabolic syndrome.
  Shah IM, et al.,Diabetes Res Clin Pract. 2007 Aug 16; [Epub ahead of print]

Diet, Nutrition and Metabolism

• Comparative review of diets for the metabolic syndrome: implications for nonalcoholic fatty liver disease.
  (Zivkovic AM, et al., Am J Clin Nutr. 2007 Aug;86(2):285-300. Review.)
• A carbohydrate-restricted diet alters gut peptides and adiposity signals in men and women with metabolic syndrome.
  Hayes MR, et al., J Nutr. 2007 Aug;137(8):1944-50.
• Milk and dairy consumption, diabetes and the metabolic syndrome: the Caerphilly prospective study.
  Elwood PC, et al., J Epidemiol Community Health. 2007 Aug;61(8):695-8.
• C57BL/6J and A/J mice fed a high-fat diet delineate components of metabolic syndrome.
  Gallou-Kabani C, et al.,Obesity (Silver Spring). 2007 Aug;15(8):1996-2005.
• Effects of PREMIER lifestyle modifications on participants with and without the metabolic syndrome.
  Lien LF, et al.,Hypertension. 2007 Oct;50(4):609-16. Epub 2007 Aug 13.
• A randomized trial of a hypocaloric high-protein diet, with and without exercise, on weight loss, fitness, and markers of the metabolic syndrome in overweight and obese women.
  Meckling KA, et al.,Appl Physiol Nutr Metab. 2007 Aug;32(4):743-52.

Drug Therapy

• Blocking fatty acids' mystery tour: a therapy for metabolic syndrome?
  Roden M., Cell Metab. 2007 Aug;6(2):89-91.
• Targeting glucagon receptor signalling in treating metabolic syndrome and renal injury in Type 2 diabetes: theory versus promise.
  Li XC, et al, Clin Sci (Lond). 2007 Aug;113(4):183-93. Review.
• Is there a role for fibrates in the management of dyslipidemia in the metabolic syndrome?
  Barter PJ, et al., Arterioscler Thromb Vasc Biol. 2007 Aug 23; [Epub ahead of print]
• Therapeutic actions of allylmercaptocaptopril and captopril in a rat model of metabolic syndrome.
  Ernsberger P, et al.,Am J Hypertens. 2007 Aug;20(8):866-74.
• The effect of orlistat and fenofibrate, alone or in combination, on small dense LDL and lipoprotein-associated phospholipase A2 in obese patients with metabolic syndrome.
  Filippatos TD, et al., Atherosclerosis. 2007 Aug;193(2):428-37. Epub 2006 Sep 5.
• Regulatory functions of PPARbeta in metabolism: implications for the treatment of metabolic syndrome.
  Grimaldi PA. Biochim Biophys Acta. 2007 Aug;1771(8):983-90. Epub 2007 Feb 24.
• Fenofibrate therapy ameliorates fasting and postprandial lipoproteinemia, oxidative stress, and the inflammatory response in subjects with hypertriglyceridemia and the metabolic syndrome.
  Rosenson RS, et al.,Diabetes Care. 2007 Aug;30(8):1945-51. Epub 2007 May 4.

Epidemiology

• Overweight, obesity and metabolic syndrome in rural southeastern Australia.
  Janus ED, et al., Med J Aust. 2007 Aug 6;187(3):147-52.
• Considerable disagreement among definitions of metabolic syndrome for Japanese.
  Oda E, et al., Circ J. 2007 Aug;71(8):1239-43.
• Association of the estrogen receptor-alpha gene with the metabolic syndrome and its component traits in African-American families: the Insulin Resistance Atherosclerosis Family Study.
  Gallagher CJ, et al., Diabetes. 2007 Aug;56(8):2135-41. Epub 2007 May 18.
• The association of serum gamma glutamyltransferase with components of the metabolic syndrome in the Korean adults.
  Kang YH, et al.,Diabetes Res Clin Pract. 2007 Aug;77(2):306-13. Epub 2007 Mar 13.
• FABP2 Ala54Thr polymorphism and diabetes in Chilean elders.
  Albala C, et al., Diabetes Res Clin Pract. 2007 Aug;77(2):245-50. Epub 2007 Feb 12.
• Inorganic arsenic exposure and its relation to metabolic syndrome in an industrial area of Taiwan.
  Wang SL, et al., Environ Int. 2007 Aug;33(6):805-11. Epub 2007 May 3.
• HIV and metabolic syndrome: a comparison with the general population.
  Bonfanti P, et al.J Acquir Immune Defic Syndr. 2007 Aug 1;45(4):426-31.
• Education, psychosocial resources, and metabolic syndrome variables in latinas.
  Gallo LC, et al., Ann Behav Med. 2007 Aug;34(1):14-25.
• Age-specific prevalence of the metabolic syndrome defined by the International Diabetes Federation and the National Cholesterol Education Program: the Norwegian HUNT 2 study.
  Hildrum B, et al. BMC Public Health. 2007 Aug 29;7(1):220 [Epub ahead of print]
• Glycated haemoglobin as a predictor for metabolic syndrome in non-diabetic Korean adults.
  Sung KC, et al., Diabet Med. 2007 Aug;24(8):848-54.
• Waist circumference, metabolic syndrome and coronary artery disease in a Pakistani cohort.
  Wierzbicki AS, et al.,Int J Cardiol. 2007 Aug 7; [Epub ahead of print]

Exercise & Physical Activity

• Exercise and diet induced weight loss improves measures of oxidative stress and insulin sensitivity in adults with characteristics of the metabolic syndrome.
  Rector RS, et al. Am J Physiol Endocrinol Metab. 2007 Aug;293(2):E500-6. Epub 2007 May 1
• Comparison of ventilatory threshold and exercise habits between Japanese men with and without metabolic syndrome.
  Miyatake N, et al., Diabetes Res Clin Pract. 2007 Aug;77(2):314-9. Epub 2007 Jan 4.

Genetics

• Adiponectin SNP276 is associated with obesity, the metabolic syndrome, and diabetes in the elderly.
  Yang WS, et al. Am J Clin Nutr. 2007 Aug;86(2):509-13.
• The association between HTR2C gene polymorphisms and the metabolic syndrome in patients with schizophrenia.
  Mulder H, et al., J Clin Psychopharmacol. 2007 Aug;27(4):338-43.
• Interleukin1beta genetic polymorphisms interact with polyunsaturated fatty acids to modulate risk of the metabolic syndrome.
  Shen J, et al., J Nutr. 2007 Aug;137(8):1846-51.
• 11Beta-HSD type 1 expression in human adipose tissue: impact of gender, obesity, and fat localization.
  Paulsen SK, et al., Obesity (Silver Spring). 2007 Aug;15(8):1954-60.
• New metabolic phenotypes in laminopathies: LMNA mutations in patients with severe metabolic syndrome.
  Decaudain A, et al., J Clin Endocrinol Metab. 2007 Aug 21; [Epub ahead of print]
• Association of the estrogen receptor-alpha gene with the metabolic syndrome and its component traits in African-American families: the Insulin Resistance Atherosclerosis Family Study.
  Gallagher CJ, et al., Diabetes. 2007 Aug;56(8):2135-41. Epub 2007 May 18.
• Gender and genetic differences in bladder smooth muscle PPAR mRNA in a porcine model of the metabolic syndrome.
  Mattern HM, et al.,Mol Cell Biochem. 2007 Aug;302(1-2):43-9. Epub 2007 Feb 21.
• Quantitative trait loci associated with blood pressure of metabolic syndrome in the progeny of NZO/HILtJ x C3H/HeJ intercrosses.
  Nishihara E, et al. Mamm Genome. 2007 Aug;18(8):573-83. Epub 2007 Jul 20.
• Association analyses of GIP and GIPR polymorphisms with traits of the metabolic syndrome.
  Nitz I, et al.,Mol Nutr Food Res. 2007 Aug;51(8):1046-52.

Hypertension

• The metabolic syndrome in hypertension: diagnostic and therapeutic implications.
  Redon J, et al.,Curr Hypertens Rep. 2007 Aug;9(4):305-13.
• Should hypertension guidelines be changed for hypertensive patients with the metabolic syndrome?
  Segura J, et al.,J Clin Hypertens (Greenwich). 2007 Aug;9(8):595-600.

Insulin Sensitivity / Insulin Resistance

• Clinical diagnosis of metabolic syndrome 1. Metabolic syndrome and insulin resistance.
  Ura N, et al., Intern Med. 2007;46(16):1283-4. Epub 2007 Aug 15. No abstract available.
• Insulin resistance and the metabolic syndrome-or the pitfalls of epidemiology.
  Yudkin JS.Diabetologia. 2007 Aug;50(8):1576-86. Epub 2007 Jun 26.

Metabolic Syndrome in Women

• Metabolic syndrome in normal and complicated pregnancies.
  Bartha JL, et al.,Eur J Obstet Gynecol Reprod Biol. 2007 Aug 4; [Epub ahead of print]

Non-Alcoholic Fatty Liver Disease

• Has natural selection in human populations produced two types of metabolic syndrome (with and without fatty liver)?
  Caldwell SH, et al., J Gastroenterol Hepatol. 2007 Jun; 22 Suppl 1:S11-9.
• Evaluation and management of obesity-related nonalcoholic fatty liver disease.
  Nugent C, et al.,Nat Clin Pract Gastroenterol Hepatol. 2007 Aug;4(8):432-41. Review.
• Fatty liver. A novel component of the metabolic syndrome.
  Kotronen A, et al., Arterioscler Thromb Vasc Biol. 2007 Aug 9; [Epub ahead of print]

Obesity

• Is central obesity a good predictor of carotid atherosclerosis in Japanese Type 2 Diabetes with metabolic syndrome?
  Yasuda T, et al.,Endocr J. 2007 Aug 30; [Epub ahead of print]
• Microvascular dysfunction in obesity: a potential mechanism in the pathogenesis of obesity-associated insulin resistance and hypertension.
  Jonk AM, et al. Physiology (Bethesda). 2007 Aug;22:252-60.
• BMI versus the metabolic syndrome in relation to cardiovascular risk in elderly Chinese individuals.
  He Y, et al.,Diabetes Care. 2007 Aug;30(8):2128-34. Epub 2007 Apr 27
• Effect of weight loss on LDL and HDL kinetics in the metabolic syndrome: Associations with changes in plasma retinol-binding protein-4 and adiponectin levels.
  Ng TW, et al.,Diabetes Care. 2007 Aug 8; [Epub ahead of print]

PCOS

• Polycystic ovary syndrome.
  Norman RJ, et al. Lancet. 2007 Aug 25;370(9588):685-97. Review.
• Retinol-binding protein 4 levels are elevated in polycystic ovary syndrome women with obesity and impaired glucose metabolism.
  Hahn S, et al. Eur J Endocrinol. 2007 Aug;157(2):201-7.
• Insulin sensitivity after metformin suspension in normal-weight women with polycystic ovary syndrome.
  Palomba S, et al. J Clin Endocrinol Metab. 2007 Aug;92(8):3128-35. Epub 2007 May 22.
• C-reactive protein before and after weight loss in overweight women with and without polycystic ovary syndrome.
  Moran LJ, et al. J Clin Endocrinol Metab. 2007 Aug;92(8):2944-51. Epub 2007 May 15.

Pediatrics

• Insufficient growth hormone secretion is associated with metabolic syndrome after allogeneic stem cell transplantation in childhood.
  Taskinen M, et al.,J Pediatr Hematol Oncol. 2007 Aug;29(8):529-34.
• Association between abnormal liver function and risk factors for metabolic syndrome among freshmen.
  Tsai PY, et al, J Adolesc Health. 2007 Aug;41(2):132-7.
• Serum retinol-binding protein 4 concentration and its ratio to serum retinol are associated with obesity and metabolic syndrome components in children.
  Aeberli I, et al., J Clin Endocrinol Metab. 2007 Aug 28; [Epub ahead of print]
• Insulin resistance: link to the components of the metabolic syndrome and biomarkers of endothelial dysfunction in youth.
  Lee S, et al.,Diabetes Care. 2007 Aug;30(8):2091-7. Epub 2007 May 2.
• Metabolic abnormalities, insulin resistance, and metabolic syndrome in children with primary hypertension.
  Litwin M, et al.,Am J Hypertens. 2007 Aug;20(8):875-82.
• Metabolic syndrome in childhood predicts adult cardiovascular disease 25 years later: the Princeton Lipid Research Clinics Follow-up Study.
  Morrison JA, et al., Pediatrics. 2007 Aug;120(2):340-5.
• Childhood metabolic syndrome and its components in premature adrenarche.
  Utriainen P, et al.,J Clin Endocrinol Metab. 2007 Aug 14; [Epub ahead of print]

Prothrombotic State

• Identifying patients at risk for microalbuminuria via interaction of the components of the metabolic syndrome: a cross-sectional analytic study.
  Franciosi M, et al. Clin J Am Soc Nephrol. 2007 Sep;2(5):984-91. Epub 2007 Aug 5.
• Multimarker approach to evaluate the incidence of the metabolic syndrome and longitudinal changes in metabolic risk factors: the Framingham Offspring Study.
  Ingelsson E, et al. Circulation. 2007 Aug 28;116(9):984-92. Epub 2007 Aug 13.
• Inter-relationships of interleukin-6, cardiovascular risk factors and the metabolic syndrome among older men.
  Wannamethee SG, et al, J Thromb Haemost. 2007 Aug;5(8):1637-43. Epub 2007 Jun 1.

Renal Function / Kidney Disease

• Low urine pH: a novel feature of the metabolic syndrome.
  Maalouf NM, et al. Clin J Am Soc Nephrol. 2007 Sep;2(5):883-8. Epub 2007 Aug 16.
• Associations of body size with metabolic syndrome and mortality in moderate chronic kidney disease.
  Kwan BC, et al. Clin J Am Soc Nephrol. 2007 Sep;2(5):992-8. Epub 2007 Aug 16.
• Relationship between hyperuricemia and metabolic syndrome.
  Chen LY, et al., J Zhejiang Univ Sci B. 2007 Aug;8(8):593-8.
• Metabolic syndrome in childhood predicts adult cardiovascular disease 25 years later: the Princeton Lipid Research Clinics Follow-up Study.
  Morrison JA, et al.,Pediatrics. 2007 Aug;120(2):340-5.
• Are patients who have metabolic syndrome without diabetes at risk for developing chronic kidney disease? Evidence based on data from a large cohort screening population.
  Rashidi A, et al., Clin J Am Soc Nephrol. 2007 Sep;2(5):976-83. Epub 2007 Aug 8.

Risk Factors

• Are patients who have metabolic syndrome without diabetes at risk for developing chronic kidney disease? Evidence based on data from a large cohort screening population.
  Rashidi A, Clin J Am Soc Nephrol. 2007 Sep;2(5):976-83. Epub 2007 Aug 8.
• Association between abnormal liver function and risk factors for metabolic syndrome among freshmen.
  Tsai PY, et. al., J Adolesc Health. 2007 Aug;41(2):132-7.
• Low urine pH: a novel feature of the metabolic syndrome.
  Maalouf NM, et al., Clin J Am Soc Nephrol. 2007 Sep;2(5):883-8. Epub 2007 Aug 16.
• Interleukin-10 associates with adiponectin predominantly in subjects with metabolic syndrome.
  Nishida M, et al., Circ J. 2007 Aug;71(8):1234-8.
• Is metabolic syndrome a risk factor for colorectal adenoma?
  Kim JH, et al., Cancer Epidemiol Biomarkers Prev. 2007 Aug;16(8):1543-6.
• A complex web of risks for metabolic syndrome: race/ethnicity, economics, and gender.
  Salsberry PJ, et al.,Am J Prev Med. 2007 Aug;33(2):114-20.

Sleep Disorders

• Lower central serotonergic responsivity is associated with preclinical carotid artery atherosclerosis.
  Stroke. 2007 Aug;38(8):2228-33. Epub 2007 Jul 12.
• Effect of sleep apnea syndrome on the circadian profile of cortisol in obese men.
  Dadoun F, et al. Am J Physiol Endocrinol Metab. 2007 Aug;293(2):E466-74. Epub 2007 May 15
• Relationship of metabolic syndrome and obstructive sleep apnea.
  Parish JM, et al., J Clin Sleep Med. 2007 Aug 15;3(5):467-72.