2003

Up one level

Low density lipoprotein size and cardiovascular disease: a reappraisal. (Clinical Review 163).

The authors comprehensively review the literature on LDL size and cardiovascular disease from epidemiology to pathophysiology.

LDL particles containing apolipoprotein C-III are independent risk factors for coronary events in diabetic patients.

This epidemiological study identified an LDL particle type that had apolipoprotein C-III as the strongest independent lipoprotein predictor of coronary events in Type 2 diabetic patients.

NCEP-defined metabolic syndrome, diabetes, and prevalence of coronary heart disease among NHANES III participants age 50 years and older.

Although diabetes is associated with an increased risk of coronary heart disease, results of this study clearly showed that diabetes is a heterogeneous condition. In the NHANES III database, the prevalence of coronary heart disease among patients with diabetes was only increased among those meeting the NCEP-ATP III criteria for the metabolic syndrome (19.2%). Furthermore, nondiabetic individuals with the metabolic syndrome also showed an increased prevalence of coronary heart disease (13.9%).

Prevalence and characteristics of the metabolic syndrome in the San Antonio Heart and Framingham Offspring Studies.

This study reports the prevalence of the Metabolic Syndrome in the San Antonio and Framingham Offspring Study. The Metabolic Syndrome was defined by using both the NCEP-ATP III and the WHO criteria. Rates were highest in Mexican-American women and lowest in white women. Importantly, regardless of the definition, the Metabolic Syndrome was associated with elevated levels of insulin resistance and predicted coronary heart disease risk.

The incidence and persistence on the NCEP (National Cholesterol Education Program) metabolic syndrome. The French D.E.S.I.R. study

Epidemiological data form a French survey (DESIR) showing some specificities in France in the prevalence of abnormalities defining the Metabolic Syndrome.